The Délįnę Got'įnę Government is comprised of the former Deline First Nation, Deline Land Corporation and Deline Charter Community. It operates according to its Final Self-Government Agreement, the Sahtu Dene Métis Land Claim Agreement, and its own Aeado (Constitution) and laws. It is part of the Sahtu Region.

The Akaitcho Territory Government (ATG) represents the collective social, political, cultural, environmental and economic interests of its constituent First Nations.

The Fort Simpson Métis are based in the Fort Simpson community in the Dehcho Region. They are part of the Dehcho First Nations.

The Fort Providence Métis Council represents the interests of the Indigenous Métis/Dene Descendants of the Fort Providence area, part of the Dehcho First Nations.

The West Point First Nation is comprised of the Ts'ueh Nda community, including Métis and Dene people who have moved their families to take advantage of the Great Slave Lake fishing industry. The community is within the municipal boundaries of Hay River in the Dehcho Region and is part of the Dehcho First Nations.

Sambaa K'e First Nation is located in Sambaa K'e (place of trout) formerly known as Trout Lake, in the Dehcho region. They are part of the Dehcho First Nations. The population is 92 people.

The Pehdzeh Ki First Nation is located in the community of Wrigley in the Dehcho Region and has over 300 band members. It is part of the Dehcho First Nations.

The Nah?a Dehé Dene Band is based in Nahanni Butte in the Dehcho Region, which has a population of 116 people. The Band is part of the Dehcho First Nations.

Łíídlįį Kúé First Nation is based in the community of Fort Simpson or Łíídlįį Kúé, "the place where rivers come together". They are part of the Dehcho First Nations. 

The Ka’a’gee Tu First Nation, meaning between the willows, is a community is located on Lake Kakisa, southeast of Fort Providence in the Dehcho Region. They are part of the Dehcho First Nations.